1911 Encyclopædia Britannica/Leontiasis Ossea

LEONTIASIS OSSEA, a rare disease characterized by an overgrowth of the facial and cranial bones. The common form is that in which one or other maxilla is affected, its size progressively increasing both regularly and irregularly, and thus encroaching on the cavities of the orbit, the mouth, the nose and its accessory sinuses. Exophthalmos gradually develops, going on later to a complete loss of sight due to compression of the optic nerve by the overgrowth of bone. There may also be interference with the nasal respiration and with the taking of food. In the somewhat less common form of this rare disease the overgrowth of bone affects all the cranial bones as well as those of the face, the senses being lost one by one and death finally resulting from cerebral pressure. There is no treatment other than exposing the overgrown bone, and chipping away pieces, or excising entirely where possible.