seven years, and had had diarrhoea, with constant pain in the abdomen for two years. 1861. Dr. C. Ellis.
2303. A portion of small intestine, thickened by encephaloid
infiltration. Many portions of this intestine were simi- larly affected ; and particularly the duodenum at its origin. Also the caecum.
From a woman, set. twenty-three years, who had occa- sionally had difficulty of digestion for some years ; and constantly the last six or seven months. Pain, with sense of fulness in epigastrium, constant. No vomiting until quite late in the disease. (Med. Jour. Vol. LXVI. p. 233.) 1862. Dr. C. Ellis.
2304. Disorganization of the caecum, commencing at the valve, in. It had a foul and very malignant look, though there were none of the usual appearances of cancer.
From a lady, about fifty years of age, and who had been sick about eight months. A silver-coated, and unmistaka- bly assafostida pill that had been taken about six weeks before, was found at the seat of the disease. 1850.
Dr. J. B. S. Jackson.
2305. A portion of the arch of the colon, and of the sigmoid flexure, firmly adherent by encephaloid disease, and com- municating freely with each other. There was, also, the same disease in the liver.
From a gentleman, set. sixty-seven years, who was at- tacked about a year before his death with pain in the abdo- men, followed by vomiting and emaciation ; and a tumor in the left iliac region. He improved afterward so as to attend to his duties in the Legislature ; but died at last exhausted by his disease. (Med. Jour. Vol. LXV. p. 271.) 1861. Dr. C. Ellis.
2306. Cancer of the large intestine. At the junction of the sig- moid flexure and the rectum the canal was closely constricted by a circular growth, which involves from 1 to 2 in. of the wall, the thickness of which is increased to a quarter of an inch. The mucous surface is red, but apparently smooth. The subrnucous cellular coat was thickened, firm, and of a whitish color. Muscular coat thickened and striated for
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