SAYRE 1022 SCHADLE recognition of his contributions to medical science. In 1876 when he demonstrated his method of hip joint excision before the International Medical Congress in Philadelphia, Professor Lister remarked "I feel that this demonstra- tion would of itself have been a sufficient reward for my vo3'age across the Atlantic." In the beginning he was severely criticised for opening suppurating joints, and in his orthopedic surgery speaking of hip joint resec- tion, he says, "I feel that by the time this operation has been recognized as proper that the profession will have learned so well how to diagnosticate the disease in its early stages and institute proper treatment for its arrest as to render this operation almost unnecessary," and this has turned out to be the case. In the treatment of Pott's disease of the spine and of rotary lateral curvature, Dr. Sayre's originality was also shown, and the British Medical Journal speaking of his work says, "Time, which tries all things, has set its seal of emphatic and general approval both on the principles and methods , which Dr. Sayre having eminently devised, has ably illustrated, and successfully carried into prac- tice. He has removed a great mass of pain- ful, tedious, and almost incurable complaints into the region of curable and easily managed affections. He has substituted a simple and practical method within the reach of every practitioner for costly, complicated, and heavy mechanical devices which were accessible only to the few, and which only imperfectly and occasionally fulfilled their objects." "Few men have in their generation accom- plished so much for the relief of humanity, and his name will go down to posterity with that of Marion Sims (q. v.), as amongst the most distinguished benefactors whom the American Medical Profession has produced for the glory of medicine and the good of mankind during this century." As a lecturer Dr. Sayre was one of the most forceful and convincing that this coun- try has produced, and it is interesting to note that his first public appearance was in 1824 when Lafayette revisited this country, and Master Lewis A. Sayre, aged four years and six months, recited a poem in his honor com- posed by Mr. John T. Durthick, principal of the Madison Academy (named after Presi- dent Madison) at Bottle Hill, New Jersey, all of which is duly recorded in the Paladium of Liberty published in that village. Dr. Sayre married in 1849 Eliza Ann Hall, daughter of Charles Henry Hall, of Harlem, New York, whose ancestor settled at Charles- town, Massachusetts, in 1630. They had four children, Charles Henry Hall, Lewis Hall, Mary Hall, and Reginald Hall. The boys all studied medicine. The eldest died in 1890, and the second in 1890, having married Alice Pomeroy, and leaving three children, William Pomeroy Sayre, Lewis Albert Sayre, and Frances Sayre Bryan. Dr. Sayre's wife died in 1894, the daughter and the youngest son survived their father, who died September 21,. 1900. Reginald H. Sayre. Private sources. There is a Portrait in the Surg. -gen's. Library at Wash., D. C. Schadle, Jacob E. (1849-1908) Jacob E. Schadle, laryngologist, was of German ancestry and was born at Jersey Shore, Pennsylvania, June 23, 1849. He graduated from Jefferson Medical College in 1881, and practised first in a Friends' settle- ment at Pennsdale, in central Pennsylvania. After two years he moved to Shenandoah, Pennsylvania, and six years later came to St. Paul. It was during his residence in Shenandoah, and while acting as lazaret physician, that he made a record by the skill and courage which he displayed in the handling of a widespread epidemic of smallpox and stamp- ing out the disease. In 1885 he reported the successful treat- ment of three cases of mushroom poisoning by administering large doses of atropine. This was the first instance of the use of atropine as an antidote for amanitine poisoning. Schadle had, for years, been the leader in his specialty in the Northwest. He was re- markably deft in the manipulation of instru- ments in the throat and nose, and as an oper- ator he had few superiors; he invented a number of surgical instruments which are now in general use. Schadle was a frequent and highly valued contributor to the medical jour- nals of this country. His articles include: "Empyema of the Accessory Sinuses of the Nose"; "Erosions and Ulcerations of the Tri- angular Cartilage of the Septum" ; "Adenoid Growths in Children" ; "Relationship Between Diseases of the Nose and Throat and Gen- eral Diseases"; "History of Medicine"; "The Relation of Antral Sinusitis to Hay-fever and Asthma." He had for several years been engaged in the study of the etiology and treatment of hay-fever, and had advanced an entirely new theory as to the cause of this disease, which he had hoped to elaborate at the meeting of
