members: for it thickeneth the bloude, that it fleete not from digeſtion, by cleerneſſe and thinneſſe. The ſecond parte is ſent to the ſplene, for neede and alſo for helpe. It needeth, both for cleanſing of the bodie and the ſplene: it is a helpe, that it flowe into the mouth of the ſtomacke, and to make it ſtrong and thicke, and make it to itch, and ſo to wake hunger and deſire of féeding. That parte of melanchloy, that is ſuperfluitie of bloud, paſſeth to the ſplene, and that that goeth from the ſplene, néedeth not to the féeding of the ſplene, and as redde Cholera helpeth the ſtomacke to put off ſuperfluitie downward, either inwarde: ſo melancholy helpeth the vertue of appetite aboue. It is called the dregs of bloud, more verely then Cholera, or fleame, for it ſoketh and is ſeperated from bloud, as the thickneſſe of vryne, or dregges of @yrour. Nothing ſweeteth neither commeth out of fleame, for the clammineſſe thereof, nor lykewiſe of Cholera, for the ſubſtitie and cléereneſſe thereof: & therfore it is not called the dregges of Cholera, neither of fleame. The vnkindlye melancholy, is not as dregs or groundes of a thing, but as burning of aſhes, and that falleth by theſe meanes: Heat working ouermuch in ye ſubſtaunce of fleme, burneth it: and by ouermuch burning, turneth it into burned Cholera. And if the humour be firſt ſubtill and watrye, when it is burnt, it is made ſalte: and if it be troubled and thicke, it draweth to ſowreneſſe ward: and if the bloud bée burnt and tourned into aſhes, the aſhes thereof are ſalte, with a lyttle ſweeteneſſe: and when kind melancholy is burnt, the burning or aſhes therof, is ſower as vineger. And if it fall vpon the earth, it boyleth, and the ſmel thereof is heauie and ſower as vineger, ye which flyes ſhun and voyde for horrible ſauor thereof, and the ſowreſt part thereof is worſt. And if the ſubſtaunce thereof bée boyſtous and thicke, when melancholy is burnt the aſhes thereof is leſſe ſower with a lyttle ſharpneſſe, the which when it falleth vpon the earth, boyleth leſſe, & grieueth the members leſſe, and is not ſo malytious nor ſo venemous, neyther slayeth ſo ſoone as the firſt. This blacke Cholera is enemie to kind, and hath aptly euill deedlye qualyties, and breedeth euills incurable, as canker, lepry, & other ſuch. By burning of fleame, of bloud, & of kinde melancholy, vnkinde and worſt melancholy is bread: and when by ſeething the bloud is bred of fleame, and Cholera of bloud by ſtrong heate, and of Cholar, melancholy: and of that burning, that infecteth the kindly humour, that worſt humour is happely bread, as Coa. ſaith li. pri. ca. 24. Of this humour hauing maſterie in any bodye, theſe bee the ſignes and tokens. Firſt the colour of the ſkinne chaungeth into blacke or bloo: ſower ſauour, ſharpe and earthye is felt in the mouth: By the qualytie of the humor, the patient is faint, and fearfull in heart without cauſe: and ſo all that haue this paſſion, are fearefull without cauſe, and oft ſory, and that is through the melancholy humour, yt conſtraineth and cloſeth the heart: and ſo if we aſke of ſuch heauie folkes what they ſcare, or wherefore they be ſorye, they haue none aunſwere. Some ſuppoſe that they ſhoulde dye in ſome ſodaine vyolence: Some dread emnitie of ſome man: Some loue and deſire death. Wherfore in li. Paſſionem Galen ſaith: It is no wonder, though they that ſuffer Choleram nigram be very ſorie, & haue ſuſpition of death. For nothing is more dredfull outward in the body than darkneſſe. And ſo when any obſcure thing heleth the brayne, as melancholy fleme, the patient muſt needes dread: for he beareth with him the cauſe why he ſhoulde dread. And therefore he dreameth dredfull darke dreames, and very ill to ſee, & of ſtinking ſauour and ſmell, of which is bred Paſsio melancholia. Alſo it commeth of a madneſſe, and of diſpoſition of melancholy, when ſuch haue lyking and laugh alway of ſorrowfull things, and make ſorow and dolor for ioyful things. Alſo ſuch holde their peace when they ſhould ſpeake, and ſpeake too much when they ſhould be still. Alſo ſome deeme themſelues that they be earthen veſſels, and feare to be touched, lea@t they break. And ſome thinke that they cloſe ye world