344
\1RGINIA BIOGRAPHY
with the })lague in Lisbon, where he met
Bishop Carroll, of Maryland, who persuaded
him to come to America. He was in Fred-
erick county, Virginia, before 1747, the date
of his first land grant, and was active in the
Indian wars, and held a commission in the
Virginia line in 1775. He died near Win-
chester, \'irginia, in 1806, and was buried
under the old Catholic church in Winches-
ter, which he Iniilt and gave to that de-
nomination. He married Elizabeth Wheeler,
of Prince George county, Maryland, and left
surviving issue.
(IV) Edward (2) McGuire, son of Ed- ward (i) McGuire, the immigrant, and Elizabeth (Wheeler) McGuire, was born in 1768, at or near Winchester, Frederick county, Virginia. He always lived in Win- chester ; was a merchant and had stores in Alexandria and Norfolk, A'irginia ; and in Wilmington. North Carolina. Also owned large farms in Frederick county and else- where in Virginia. In politics he was a Federalist, and was a member of the Epis- copal church. He married Elizabeth Holmes, born in 1794, daughter of Colonel Joseph Holmes, of Winchester, Virginia. They had issue, namely: Rebecca, Milicent, Hugh Holmes, Edward D., William David, of whom more hereafter ; David Flolmes, John.
(V) Dr. William David IMcGuire, son of Edward (2) and Elizabeth (Holmes) Mc- Guire, was born February 23, 1810, at Win- chester, Frederick county, Virginia. He graduated from the University of Pennsyl- vania Medical School as M. D. in 1830, and soon afterward began the practice of medi- cine at Winchester, Virginia, but after a few years gave up his profession and be- came a planter near Winchester. Before the civil war he was a Whig, but after the war a Democrat ; served as presiding justice in the justice court of his county for some years. Died February 4. 1877, at or near Winchester, X'irginia.
He married (first) Lucy Catherine Ware, in 1833, who had issue several children, of whom only one daughter lived to maturity, to wit: Elizabeth Holmes, born in 1834 in Clarke county, Virginia. He married (sec- ond) Nancy Boyd Moss, daughter of Cap- tain William and Gertrude (Flolmes) Moss, February 16, 1841, in Fairfax county, Vir- ginia. She was born December 4. 1818, at Aspen Hill, Fairfax county. \'irginia : her
mother, Gertrude (Holmes) Moss, was a
daughter of Colonel Joseph Holmes, of
Winchester, Virginia, and her father. Cap-
tain William Moss, was a son of Ann Minor
by Captain John Moss, of Fairfax county,
Virginia, who was an officer in the revolu-
tionary war. Said last mentioned John
Moss was a son of Thomas Moss, of Fair-
fax county, Virginia, who was the son of
Thomas Moss, of Westmoreland county,
Virginia, and the latter a descendant of Ed-
ward Moss, of York county, Virginia, whose
father came to Virginia in 1625, from Staf-
fordshire, England. Dr. William David
McGuire and his wife had eleven children,
of whom only the following mentioned sur-
vived to maturity, namely : Margaretta
Holmes, born January 12, 1844; Nannie
W^ilmer, born Alay 30, 1854; Evelyn Parker,
born November 7, 1857 > William Edward;
of whom more hereafter.
(VI) Dr. William Edward McGuire, son of William David and Nancy Boyd (Moss) McGuire, was born March, i860, at Nor- wood, near Berryville, in Clarke county, A'irginia. He attended the Berryville Acad- emy, and the Berryville High School, after which he studied medicine at the University of Virginia, and graduated therefrom as M. D. in 1886; however, prior to that time, he had spent three years as a civil engineer in the employ of the Pennsylvania Railroad Company. After his graduation in medicine he began practice in Richmond, Virginia, where he has continued as a physician and surgeon since that time. He was at one time president of the Richmond Academy of Aledicine; from 1894 to 191 1, professor of gynecology in the University College of Medicine at Richmond. Virginia ; professor of clinical medicine in the same institution from 191 1 to 1913, and thereafter professor of clinical medicine in the Medical College of Virginia, at Richmond. Virginia. He is a member of the Virginia State Medical Society, the Southern Medical and Surgical Societ}', and of the American Medical Asso- ciation. In politics he is a Democrat, a member of the Protestant Episcopal church, also of the Westmoreland Club, of Rich- mond, and of the Country Club of Virginia.
Dr. I\Ic(juire married Mary Stuart Mc- (Juire. daughter of Dr. Hunter Holmes and Mary (Stuart) McGuire, October 9, 1894, at Richmond, \irginia. She was born De- cember 3, 1872, in Richmond, \"irginia, and
