describe the bounds, if any, beyond which digestion has no influence. The digestive apparatus is commonly spoken of as including the alimentary canal and those important glands that contribute secretions to the successive processes involved; but, as absorption and assimilation, on the one hand, and formation and withdrawal of waste products, on the other, are so nearly related to preliminary digestion, it is impossible to form a clear conception of disease of the digestive organs without observing the state of other and contributory parts of the body. While it makes for simplicity of description to exclude those organs not commonly grouped with the digestive apparatus, this does not result in a correct understanding, and therefore, if an explanation is to be found, not only for a disturbed physiological state, but also, in instances, for structural changes in the digestive organs, the field must be widened, and study be directed to the nervous system, including its physical manifestations, to the fluids of the body, to the rebuilding and breaking-down of tissue, and to the eliminative functions as well. Unconsciously, a great part of the importance of this general view is perhaps recognized when it is assumed