discussed of which Shakespeare never heard. He does not speak of many sorts of fungi, of slime molds, microbes; he knew nothing about these. The microscope had hardly been invented, and the unseen world was as yet largely personified. And yet Shakespeare has not failed to note the visible signs of some of our microscopic forms. Critics have wasted their time and the patience of mankind in an effort to identify Hebona, the "leperous distilment" poured into the porches of the royal ear. Almost profitless are such discussions. Yet we may note that we have here to do with an effect; the means of producing it need not be too closely questioned. Before the rush of action, the weird setting, the voice of an apparition, the excited audience cares not what the mysterious vial may contain—ebony, henbane, yew, or whether it were entirely empty. What is called for is a speedy and mysterious taking off. Had the scene been laid in Italy, the effect had been reached by the fateful prick of a jeweled pin, some ring upon a Borgian finger whose pressure was the paralysis of death. But the king died of no such curari. Note the symptoms (Hamlet, i, 5, 64-73):
"The leperous distilment; whose effect
Holds such an enmity with blood of man
That swift as quicksilver it courses through
The natural gates and alleys of the body,
And with a sudden vigour it doth posset
And curd, like eager droppings into milk,
The thin and wholesome blood; so did it mine;
And a most instant tetter barked about.
Most lazar-like, with vile and loathsome crust.
All my smooth body."
These are the symptoms of blood-poisoning, vividly portrayed; of some contagion, communicable by infection. In foul old London Shakespeare had doubtless seen endemic, zymotic diseases of every description, and drew his picture from the life. Royal blood is notoriously unsound, royal habit leaves the porches of royal ears especially exposed. On our supposition the vial need not have contained very much, not even ebony. The dramatist had plenty of mystery ready to his hand, and the Hebona is perhaps intentionally ambiguous. Bacterial diseases were of old called plagues; they fell from heaven. Listen to King Lear:
"Now, all the plagues that in the pendulous air
Hang fated o'er men's faults, light on my daughters!"
Or Caliban:
"All the infections that the sun sucks up
From bogs, fens, flats, on Prosper fall and make him
By inch-meal a disease!"
