The Players
| Philo Vance | William Powell | |
| Alice LaFosse | Jean Arthur | |
| Jimmie Spottswoode | James Hall | |
| "The Canary" | Louise Brooks | |
| Charles Spottswoode | Charles Lane | |
| John Cleaver | Lawrence Grant | |
| Dr. Ambrose Lindquist | Gustav von Seyffertitz | |
| District Attorney Markham | Captain E. H. Calvert | |
| Sergeant Heath | Eugene Pallette | |
| Tony Skeel | Ned Sparks | |
| Louis Mannix | Louis John Bartels | |