- Sutro, Adolph Heinrich Joseph
- Sutter, John Augustus
- Swan, Joseph Rockwell
- Swartwout, Robert
- Swartz, Joel
- Swartz, Olaus
- Swatane
- Swisshelm, Jane Grey
- Symmes, John Cleves
- Symmes, Zechariah
- Symonds, William Law
- Tafel, Johann Friedrich Leonhard
- Taft, Alphonso
- Taft, Lorado
- Tammany
- Taney, Roger Brooke
- Taylor, Bayard
- Teall, Francis Augustus
- Techotlalatzin
- Tecto, Juan de
- Tecumseh
- Tecum-Uman
- Teedyuscung
- Tegakouita, Catharine
- Teganakoa, Stephen
- Teganissorens
- Tellkampf, Johann Ludwig
- Tenney, William Jewett
- Ternaux, Henry
- Terry, William
- Terry, William Richard
- Teschemacher, James Englebert
- Tessier, Ulric Joseph
- Teste, Lucien Auguste
- Tetinchoua
- Tetlepanquetzal
- Têtu, Louis David Henri
- Tetzotzomoc
- Thacher, George
- Thaxter, Adam Wallace
- Thaxter, Celia
- Thayer, Nathaniel
- Thayer, Simeon
- Thayer, Sylvanus
- Thayer, Thomas Baldwin
- Theaker, Thomas Clarke
- Thienpont, Émanuel
- Thiéry de Ménonville, Nicolas Joseph
- Thoburn, James Mills
- Thom, George
- Thomas, George Henry
- Thomas, Isaiah
- Thomas, Jane
- Thomas, Theodore
- Thoreau, Henry David
- Thorfinn
- Thurston, Asa
- Ticknor, Elisha
- Ticknor, George
- Ticknor, William Davis
- Tiffin, Edward
- Tizoc
- Tlalhuicole
- Tlaxpanquizqui
- Tocqueville, Alexis ..., Count de
- Tod, George
- Todd, Alpheus
- Todd, Charles Burr
- Tom
- Tomes, Robert
- Tomlinson, Gideon
- To-mo-chi-chi
- Torre-Tagle, José Bernardo, Marquis de
- Torrey, Bradford
- Torrey, Charles Turner
- Torrey, John
- Torrubia, José
- Totepehu
- Totiri, Stephen
- Totoquiyauhtzin
- Toussaint, Dieudonné Gabriel
- Toussaint, Dominique François
- Trask, George
- Travis, William Barrett
- Treadwell, Daniel
- Trimble, Allen
- True, Charles Kittridge
- Trumbull, Benjamin
- Tschudi, Johann Jakob von
- Tsondatsaa, Charles
- Tubman, Harriet
- Tucker, Thomas Tudor
- Tuckerman, Joseph
- Tudor, William
- Tufts, Charles
- Tufts, Cotton
- Tufts, John
- Tuomey, Michael
- Tupac-Amaru
- Tupac Inca Yupanqui
- Tupper, Benjamin
- Tupper, Charles
- Tyrker
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- Uffenbach, Bernard von
- Uhland, Maximilian
- Uhle, Albrecht Bernhard
- Uhler, Philip Reese
- Ullmann, Daniel
- Ulphilas, Herman
- Ulrich, Charles Frederick
- Umbscheiden, Franz
- Vance, Joseph
- Vanderbilt, Cornelius
- Van Nostrand, David
- Van Rensselaer, Killian
- Van Rensselaer, Mariana Griswold
- Varnhagen, Francisco Adolpho de
- Varnum, James Mitchel
- Varona, Enrique José
- Varrick, James
- Vasey, George
- Verrill, Addison Emory
- Verschoor, Julius Wilhelm Van
- Vertin, John
- Very, Jones
- Vicente y Bennazar, Andres
- Villard, Henry
- Vinton, Samuel Finley
- Vogué, Jean Pierre de
- Vollmering, Joseph
- Vose, George Leonard
- Waddel, James
- Waggamann, George Augustus
- Wagner, Daniel Christian
- Wagner, John
- Wagner, Moritz Friedrich
- Wagner, Webster
- Wagner, William
- Wainwright, Jonathan Mayhew
- Wainwright, Richard
- Waite, Carlos Adolphus
- Waite, Charles Burlingame
- Waite, Henry Matson
- Waite, Henry Randall
- Wakefield, Cyrus
- Wakefield, Nancy Amelia Woodbury Priest
- Wakeley, Joseph B.
- Walbach, John Baptiste de Barth
- Walbridge, Arthur Dewey
- Waldeck, Jean Frédéric de
- Walden, John Morgan
- Waldersee, Mary
- Waldseemüller, Martin
- Waldstein, Charles
- Wales, James Albert
- Walker, Amasa
- Walker, James
- Walker, Jonathan
- Walker, Katherine Kent Child
- Walker, Timothy (clergyman)
- Walker, Timothy (jurist)
- Walker, William (merchant)
- Walker, William (adventurer)
- Walker-Martinez, Carlos
- Walk-in-the-Water
- Wallack, James William
- Wangenheim, Frederick Adam Julius
- Ward, Richard
- Warren, Gouverneur Kemble
- Warren, William (actor)
- Washington, Booker Taliaferro
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- Weaver, Jonathan
- Webb, Samuel Blatchley
- Webb, Thomas
- Webb, Thomas Smith
- Webber, Charles Wilkins
- Webber, Samuel
- Weber, Gustav C. E.
- Weber, Max
- Weber, Paul
- Webster, Albert Falvey
- Webster, Ebenezer
- Webster, John White
- Webster, Noah
- Weed, Thurlow
- Weems, Mason Locke
- Weidemeyer, John William
- Weiss, George Michael
- Weiss, John
- Weiss, Susan Archer Talley
- Weisse, John Adam
- Weissenfels, Frederick H.
- Weitzel, Godfrey
- Welch, John
- Weld, Theodore Dwight
- Weller, John B.
- Welser, Bartholomeus
- Wentworth, William
- Wernicke, Gottlieb
- Wernwag, Lewis
- Wertmüller, Adolph Ulric
- Wesley, John
- Westerlo, Eilardus
- Westerman, Hans
- Western, Pauline Lucille
- Weston, Edward
- Weston, Henry Griggs
- Weston, Mary Catharine North
- Whalley, Edward
- Wheatley, Charles Moore
- Wheatley, Phillis
- Wheatley, Sarah
- Wheaton, Frank
- Wheaton, Henry
- Wheeler, Thomas
- Wheeler, William Adolphus
- Wheildon, William Willder
- Whitcomb, John
- White, Anthony Walton
- White, Edward Douglas
- White, Horace
- Whiting, Henry
- Whiting, Nathan
- Whiting, Samuel
- Whitman, Marcus
- Whitman, Sarah Helen
- Whitman, Walt
- Whitmarsh, Caroline Snowden
- Whitmer, David
- Whitmore, Edward
- Whitmore, William Henry
- Whitney, Adeline Dutton Train
- Whitney, Anne
- Whitney, Asa (manufacturer)
- Whitney, Asa (merchant)
- Whitney, Eli
- Whitney, James Amaziah
- Whitney, Josiah Dwight
- Whitney, Myron W.
- Whitney, Peter
- Whitney, Thomas Richard
- Whitney, William Collins
- Whittlesey, Elisha
- Wierzbicki, Felix Paul
- Willard, Abijah
- Willard, Simon (settler)
- Willard, Simon (watch-maker)
- Williamson, Isaiah Vansant
- Willich, August
- Wilson, James
- Wilson, John Laird
- Wilson, Woodrow
- Winslow, John Ancrum
- Winsor, Justin
- Winter, William
- Winthrop, John
- Wirt, William
- Wise, John (aëronaut)
- Wisser, John Philip
- Wissler, Jacques
- Wistar, Richard
- Wister, Annis Lee
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- Woedtke, Frederick William
- Woert, Jan Jacobus Sebald
- Wolf, George
- Wolf, Simon
- Wollenweber, Louis August
- Wood, George Bacon
- Wood, Reuben
- Wood, William B.
- Woodford, Stewart Lyndon
- Woodhouse, James
- Woodward, Calvin Milton
- Worcester, Noah (clergyman)
- Worcester, Noah (educator)
- Worman, James Henry
- Wormeley, Mary Elizabeth
- Worthington, Thomas
- Wouwerman, Simon van
- Wragg, William
- Wrangel, Charles Magnus von
- Wrangell, Ferdinand Petrovitch, Baron von
- Wright, Carroll Davidson
- Wright, Charles Barstow
- Wright, Chauncey
- Wright, Elizur
- Wright, Fanny
- Wright, John C.
- Wurtele, Jonathan Saxton Campbell
- Wurtz, Henry
- Xiuhtemoc I.
- Xiutlaltzin
- Xochitl
- Xolotl
- Xuárez, Pedro
- Yale, Cyrus
- Yale, Elihu
- Youmans, Edward Livingston
- Youmans, Letitia Creighton
- Young, Brigham
- Young, Thomas Lowry
- Yung Wing
- Zalinski, Edmund Louis Gray
- Zane, Ebenezer
- Zea, Francisco Antonio
- Zeilin, Jacob
- Zeisberger, David
- Zenger, John Peter
- Zerrahn, Carl
- Zeuner, Charles
- Zinzendorf, Nicholas Lewis
- Zogbaum, Rufus Fairchild
- Zollicoffer, Felix Kirk
- Zook, Samuel Kosciuzko
- Zorrilla, Francisco
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